作者：華筱玲、馮瑞鶯、黃菁瑜、謝意苹、魏希聖、沈瓊桃

題目：Association between childhood polyvictimization, telomere length, and post-traumatic stress disorder.

摘要：

Background
Child maltreatment is related to adverse psychosocial outcomes and may be associated with telomere erosion. Longitudinal research on mental health problems and telomere length (TL) in victimized children in Asian societies is scarce. In this study, we evaluated the associations of childhood polyvictimization with TL and longitudinal psychological problems.
Methods
Subcohorts were obtained from a national, proportionately stratified sample of fourth-grade Taiwanese students recruited in 2014; the sample comprised 70 high-risk group participants (experience of polyvictimization) and 129 controls (nonvictims). For these 199 participants, TL was analyzed in 2014, whereas self-report post-traumatic stress disorder (PTSD) symptom scales and psychological disorder/symptom were completed in 2014, 2016, 2018, and 2021.
Results
Childhood polyvictimization was associated with prolonged high PTSD symptom scores in 2014, 2016, 2018, and 2021. TL was significantly shorter among the polyvictims than among the nonvictims.
Conclusions
This study demonstrated an association between childhood polyvictimization and prolonged PTSD in children. Our findings also support the assertion that childhood polyvictimization is associated with telomere erosion.

主要發現：

曾遭受多重受害的兒童，在受害當年以及2、4、7年後，仍持續出現較嚴重的創傷後壓力症狀(PTSD)。此外，他們的染色體端粒也明顯比未受害的兒童短。這證實了童年多重受害不僅長期影響心理健康，還可能與生理機制有關。
註：端粒縮短是細胞老化的一種生物指標，與憂鬱症、PTSD有關，也與老化相關疾病的發病率和死亡率有關。

全文下載：https://doi.org/10.1111/ped.70101